CaKip3[2-482] - AMP-PNP in complex with a microtubule
Resolution: 2.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 7tqx
Q-score: 0.524
Hunter B, Benoit MPMH, Asenjo AB, Doubleday C, Trofimova D, Frazer C, Shoukat I, Sosa H, Allingham JS
Nat Commun (2022) 13 pp. 4198-4198 [ DOI: doi:10.1038/s41467-022-31794-3 Pubmed: 35859148 ]
- Taxol (853 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- 15r microtubule (Cellular component from Sus scrofa)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Cakip3[2-482] - amp-pnp in complex with a microtubule (Complex)
- Cakip3[2-482] - amp-pnp (Complex from Candida albicans)
- Tubulin beta-2b chain (49 kDa, Protein from Sus scrofa)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Kinesin-like protein (54 kDa, Protein from Candida albicans)
CaKip3[2-482] - ADP-AlFx in complex with a microtubule
Resolution: 2.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 7tqy
Q-score: 0.538
Hunter B, Benoit MPMH, Asenjo AB, Doubleday C, Trofimova D, Frazer C, Shoukat I, Sosa H, Allingham JS
Nat Commun (2022) 13 pp. 4198-4198 [ DOI: doi:10.1038/s41467-022-31794-3 Pubmed: 35859148 ]
- Taxol (853 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- 15r microtubule (Cellular component from Sus scrofa)
- Aluminum fluoride (83 Da, Ligand)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Cakip3[2-482] - adp-alfx (Complex from Candida albicans)
- Tubulin beta-2b chain (49 kDa, Protein from Sus scrofa)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Kinesin-like protein (54 kDa, Protein from Candida albicans)
- Cakip3[2-482] - adp-alfx in complex with a microtubule (Complex)
CaKip3[2-436] - AMP-PNP in complex with a microtubule
Resolution: 2.7 Å
EM Method: Helical reconstruction
Fitted PDBs: 7tr0
Q-score: 0.553
Hunter B, Benoit MPMH, Asenjo AB, Doubleday C, Trofimova D, Frazer C, Shoukat I, Sosa H, Allingham JS
Nat Commun (2022) 13 pp. 4198-4198 [ DOI: doi:10.1038/s41467-022-31794-3 Pubmed: 35859148 ]
- Taxol (853 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Cakip3[2-436] - amp-pnp in complex with a microtubule (Complex)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- 15r microtubule (Cellular component from Sus scrofa)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Cakip3[2-436] - amp-pnp (Complex from Candida albicans)
- Tubulin beta-2b chain (49 kDa, Protein from Sus scrofa)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Kinesin-like protein (49 kDa, Protein from Candida albicans)
CaKip3[2-436]-L2-mutant(HsKHC) - AMP-PNP in complex with a microtubule
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 7tr1
Q-score: 0.474
Hunter B, Benoit MPMH, Asenjo AB, Doubleday C, Trofimova D, Frazer C, Shoukat I, Sosa H, Allingham JS
Nat Commun (2022) 13 pp. 4198-4198 [ DOI: doi:10.1038/s41467-022-31794-3 Pubmed: 35859148 ]
- Taxol (853 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- 15r microtubule (Cellular component from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Kinesin-like protein,kinesin-1 heavy chain (46 kDa, Protein from Candida albicans)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Tubulin beta-2b chain (49 kDa, Protein from Sus scrofa)
- Cakip3[2-436] with l2 swapped with the one of hskhc, bound to amp-pnp (Complex from Candida albicans)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Cakip3[2-436]-l2-mutant(hskhc) - amp-pnp in complex with a microtubule (Complex)
- Guanosine-5'-diphosphate (443 Da, Ligand)
CaKip3[2-482] - AMP-PNP in complex with a dolastatin-10-stabilized tubulin ring
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7tr3
Q-score: 0.398
Hunter B, Benoit MPMH, Asenjo AB, Doubleday C, Trofimova D, Frazer C, Shoukat I, Sosa H, Allingham JS
Nat Commun (2022) 13 pp. 4198-4198 [ DOI: doi:10.1038/s41467-022-31794-3 Pubmed: 35859148 ]
- Magnesium ion (24 Da, Ligand)
- Cakip3[2-482] - amp-pnp in complex with a dolastatin-10-stabilized tubulin ring (Complex)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Dolastatin-10 stabilized tubulin ring (Cellular component from Sus scrofa)
- Tubulin beta-2b chain (49 kDa, Protein from Sus scrofa)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Dolastatin-10 (785 Da, Ligand)
- Cakip3[2-482] - amp-pnp (Complex from Candida albicans)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Kinesin-like protein (54 kDa, Protein from Candida albicans)
Apo CaKip3[2-482] in complex with a microtubule
Resolution: 2.7 Å
EM Method: Helical reconstruction
Fitted PDBs: 7tqz
Q-score: 0.529
Hunter B, Benoit MPMH, Asenjo AB, Doubleday C, Trofimova D, Frazer C, Shoukat I, Sosa H, Allingham JS
Nat Commun (2022) 13 pp. 4198-4198 [ DOI: doi:10.1038/s41467-022-31794-3 Pubmed: 35859148 ]
- Taxol (853 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- 15r microtubule (Cellular component from Sus scrofa)
- Apo cakip3[2-482] in complex with a microtubule (Complex)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Tubulin beta-2b chain (49 kDa, Protein from Sus scrofa)
- Apo cakip3[2-482] (Complex from Candida albicans)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Kinesin-like protein (54 kDa, Protein from Candida albicans)
Apo CaKip3[2-436]-L2-mutant(HsKHC) in complex with a microtubule
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 7tr2
Q-score: 0.501
Hunter B, Benoit MPMH, Asenjo AB, Doubleday C, Trofimova D, Frazer C, Shoukat I, Sosa H, Allingham JS
Nat Commun (2022) 13 pp. 4198-4198 [ DOI: doi:10.1038/s41467-022-31794-3 Pubmed: 35859148 ]
- Taxol (853 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- 15r microtubule (Cellular component from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Apo cakip3[2-436]-l2-mutant(hskhc) in complex with a microtubule (Complex)
- Kinesin-like protein,kinesin-1 heavy chain (46 kDa, Protein from Candida albicans)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Tubulin beta-2b chain (49 kDa, Protein from Sus scrofa)
- Cakip3[2-436] with l2 swapped with the one of hskhc, bound to amp-pnp (Complex from Candida albicans)
- Guanosine-5'-diphosphate (443 Da, Ligand)
KIF14 Motor Domain Microtubule complex
Arora K, Talje L, Asenjo AB, Andersen P, Atchia K, Joshi M, Sosa H, Allingham JS, Kwok BH
J Mol Biol (2014) 426 pp. 2997-3015 [ Pubmed: 24949858 DOI: doi:10.1016/j.jmb.2014.05.030 ]